Publicaciones 2015

PUBLICACIONES DEL IBGM EN EL AÑO 2015

(en revistas indexadas en PubMed)

 

Fisiología Celular y Molecular (CMP)

Olea E, Ribeiro MJ, Gallego-Martin T, Yubero S, Rigual R, Masa JF, Obeso A, Conde SV, Gonzalez C. 2015. The carotid body does not mediate the acute ventilatory effects of leptin. Adv. Exp. Med. Biol. 860: 379-385.

Gallego-Martin T, Agapito T, Ramirez M, Olea E, Yubero S, Rocher A, Gomez-Niño A, Obeso A, Gonzalez C. 2015. Experimental observations on the biological significance of hydrogen sulfide in carotid body Chemoreception. Adv. Exp. Med. Biol. 860: 9-16.

Prieto-Lloret J, Ramirez M, Olea E, Moral-Sanz J, Cogolludo A, Castañeda J, Yubero S, Agapito T, Gomez-Niño A, Rocher A, Rigual R, Obeso A, Perez-Vizcaino F, González C. 2015. Hypoxic pulmonary vasoconstriction, carotid body function and erythropoietin production in adult rats perinatally exposed to hyperoxia. J. Physiol. 593: 2459-2477.

Sacramento JF, Ribeiro MJ, Yubero S, Melo BF, Obeso A, Guarino MP, Gonzalez C, Conde SV. 2015. Disclosing caffeine action on insulin sensitivity: effects on rat skeletal muscle. Eur. J. Pharm. Sci. 70: 107-116.

Sacramento JF, Gonzalez C, Gonzalez-Martin MC, Conde SV. 2015. Adenosine receptor blockade by caffeine inhibits carotid sinus nerve chemosensory activity in chronic intermittent hypoxic animals. Adv. Exp. Med. Biol. 860: 133-137

Colinas O, Moreno-Domínguez A, Zhu HL, Walsh EJ, Pérez-García MT, Walsh MP, Cole WC. 2015. α5-Integrin-mediated cellular signaling contributes to the myogenic response of cerebral resistance arteries. Biochem Pharmacol. 97: 281-291.

Turczyńska KM, Swärd K, Hien TT, Wohlfahrt J, Mattisson IY, Ekman M, Nilsson J, Sjögren J, Murugesan V, Hultgårdh-Nilsson A, Cidad P, Hellstrand P, Pérez-García MT, Albinsson S. 2015. Regulation of smooth muscle dystrophin and synaptopodin 2 expression by actin polymerization and vascular injury. Arterioscler. Thromb. Vasc. Biol. 35: 1489-1497.

Fernández-Mariño AI, Cidad P, Zafra D, Nocito L, Domínguez J, Oliván-Viguera A, Köhler R, López-López JR, Pérez-García MT, Valverde MÁ, Guinovart JJ, Fernández-Fernández JM. 2015. Tungstate-targeting of BKαβ1 channels tunes ERK phosphorylation and cell proliferation in human vascular smooth muscle. PLoS One 10: e0118148.

Cidad P, Miguel-Velado E, Ruiz-McDavitt C, Alonso E, Jiménez-Pérez L, Asuaje A, Carmona Y, García-Arribas D, López J, Marroquín Y, Fernández M, Roqué M, Pérez-García MT, López-López JR. 2015. Kv1.3 channels modulate human vascular smooth muscle cells proliferation independently of mTOR signaling pathway. Pflugers Arch. 467: 1711-1722.

Rodríguez-Prados M, Rojo-Ruiz J, Aulestia FJ, García-Sancho J, Alonso MT. 2015. A new low-Ca²⁺ affinity GAP indicator to monitor high Ca²⁺ in organelles by luminescence. Cell Calcium 58: 558-564.

Senovilla L, Núñez L, de Campos JM, de Luis DA, Romero E, García-Sancho J, Villalobos C. 2015. Single-cell phenotypic characterization of human pituitary gliomas and non-functioning adenomas based on hormone content and calcium responses to hypothalamic releasing hormones. Front. Oncol. 5: 124.

Aulestia FJ, Alonso MT, García-Sancho J. 2015. Differential calcium handling by the cis and trans regions of the Golgi apparatus. Biochem. J. 466: 455-465.

Calvo-Rodríguez M, Villalobos C, Nuñez L. 2015. Fluorescence and bioluminescence imaging of subcellular Ca2+ in aged hippocampal neurons. J. Vis. Exp. 106/ doi: 10.3791/53330.

Calvo-Rodríguez M, Núñez L, Villalobos C. 2015. Non-steroidal anti-inflammatory drugs (NSAIDs) and neuroprotection in the elderly: a view from the mitochondria. Neural Regen. Res. 10: 1371-1372.

Calvo M, Sanz-Blasco S, Caballero E, Villalobos C, Núñez L. 2015. Susceptibility to excitotoxicity in aged hippocampal cultures and neuroprotection by non-steroidal anti-inflammatory drugs: role of mitochondrial calcium. J. Neurochem. 132: 403-417.

Calvo M, Villalobos C, Núñez L. 2015. Calcium imaging in neuron cell death. Methods Mol. Biol. 1254: 73-85.

Sanchez-Encinales V, Cozar-Castellano I, Garcia-Ocaña A, Perdomo G. 2015. Targeted delivery of HGF to the skeletal muscle improves glucose homeostasis in diet-induced obese mice. J. Physiol. Biochem. 71: 795-805.

López-Acosta JF, Villa-Pérez P, Fernández-Díaz CM, Román Dde L, Díaz-Marrero AR, Cueto M, Perdomo G, Cózar-Castellano I. Protective effects of epoxypukalide on pancreatic β-cells and glucose metabolism in STZ-induced diabetic mice. Islets 7: e1078053.

Diaz-Ganete A, Baena-Nieto G, Lomas-Romero IM, Lopez-Acosta JF, Cozar-Castellano I, Medina F, Segundo C, Lechuga-Sancho AM. 2015. Ghrelin's effects on proinflammatory cytokine mediated apoptosis and their impact on β-cell functionality. Int. J. Endocrinol. 2015: 235727.

Ramos-Rodriguez JJ, Jimenez-Palomares M, Murillo-Carretero MI, Infante-Garcia C, Berrocoso E, Hernandez-Pacho F, Lechuga-Sancho AM, Cozar-Castellano I, Garcia-Alloza M. 2015. Central vascular disease and exacerbated pathology in a mixed model of type 2 diabetes and Alzheimer's disease. Psychoneuroendocrinology 62: 69-79.

Visiedo F, Bugatto F, Carrasco-Fernández C, Sáez-Benito A, Mateos RM, Cózar-Castellano I, Bartha JL, Perdomo G. 2015. Hepatocyte growth factor is elevated in amniotic fluid from obese women and regulates placental glucose and fatty acid metabolism. Placenta 36: 381-388.

Jiménez-Palomares M, López-Acosta JF, Villa-Pérez P, Moreno-Amador JL, Muñoz-Barrera J, Fernández-Luis S, Heras-Pozas B, Perdomo G, Bernal-Mizrachi E, Cózar-Castellano I. 2015. Cyclin C stimulates β-cell proliferation in rat and human pancreatic β-cells. Am. J. Physiol. 308: E450-E459.

Visiedo F, Bugatto F, Quintero-Prado R, Cózar-Castellano I, Bartha JL, Perdomo G. 2015. Glucose and fatty acid metabolism in placental explants from pregnancies complicated with gestational diabetes mellitus. Reprod. Sci. 22: 798-801.

 

Inmunidad Innata e Inflamación (I3U)

Rubio JM, Rodríguez JP, Gil-de-Gómez L, Guijas C, Balboa MA, Balsinde J. 2015. Group V secreted phospholipase A2 is upregulated by IL-4 in human macrophages and mediates phagocytosis via hydrolysis of ethanolamine phospholipids. J. Immunol. 194: 3327-3339.

Santos-Nogueira E, López-Serrano C, Hernández J, Lago N, Astudillo AM, Balsinde J, Estivill-Torrús G, de Fonseca FR, Chun J, López-Vales R. 2015. Activation of lysophosphatidic acid receptor type 1 contributes to pathophysiology of spinal cord injury. J. Neurosci. 35: 10224-1035.

Pardo V, González-Rodríguez Á, Guijas C, Balsinde J, Valverde ÁM. 2015. Opposite cross-talk by oleate and palmitate on insulin signaling in hepatocytes through macrophage activation. J. Biol. Chem. 290: 11663-11677.

Torres A, Cachofeiro V, Millán J, Lahera V, Nieto ML, Martín R, Bello E, Alvarez-Sala LA. 2015. Red wine intake but not other alcoholic beverages increases total antioxidant capacity and improves pro-inflammatory profile after an oral fat diet in healthy volunteers. Rev. Clin. Esp. 215: 486-494.

Caltana L, Nieto ML, Brusco A. 2015. Oleanolic acid: a promising neuroprotective agent for cerebral ischemia. Neural Regen. Res. 10: 540-541.

Bernardo D, Durant L, Mann ER, Bassity E, Montalvillo E, Man R, Vora R, Reddi D, Bayiroglu F, Fernández-Salazar L, English NR, Peake ST, Landy J, Lee GH, Malietzis G, Siaw YH, Murugananthan AU, Hendy P, Sánchez-Recio E, Phillips RK, Garrote JA, Scott P, Parkhill J, Paulsen M, Hart AL, Al-Hassi HO, Arranz E, Walker AW, Carding SR, Knight SC. 2015. Chemokine (C-C motif) receptor 2 mediates dendritic cell recruitment to the human colon but is not responsible for differences observed in dendritic cell subsets, phenotype, and function between the proximal and distal colon. Cell. Mol. Gastroenterol. Hepatol. 2: 22-39.

Montalvillo E, Bernardo D, Martínez-Abad B, Allegretti Y, Fernández-Salazar L, Calvo C, Chirdo FG, Garrote JA, Arranz E. 2015. Increased intraepithelial Vα24 invariant NKT cells in the celiac duodenum. Nutrients 7: 8960-8976.

Crespo-Sanjuán J, Calvo-Nieves MD, Aguirre-Gervás B, Herreros-Rodríguez J, Velayos-Jiménez B, Castro-Alija MJ, Muñoz-Moreno MF, Sánchez D, Zamora-González N, Bajo-Grañeras R, García-Centeno RM, Largo Cabrerizo ME, Bustamante MR, Garrote-Adrados JA. 2015. Early detection of high oxidative activity in patients with adenomatous intestinal polyps and colorectal adenocarcinoma: myeloperoxidase and oxidized low-density lipoprotein in serum as new markers of oxidative stress in colorectal cancer. Lab. Med. 46: 123-135

Hevia A, Bernardo D, Montalvillo E, Al-Hassi HO, Fernández-Salazar L, Garrote JA, Milani C, Ventura M, Arranz E, Knight SC, Margolles A, Sánchez B. 2015. Human colon-derived soluble factors modulate gut microbiota composition. Front. Oncol. 5: 86.

 

Genética Molecular de la Enfermedad (MGD)

Ramírez BE, Sánchez A, Herreras JM, Fernández I, García-Sancho J, Nieto-Miguel T, Calonge M. 2015. Stem cell therapy for corneal epithelium regeneration following good manufacturing and clinical procedures. Biomed. Res. Int. 2015: 408495.

 

Vega A, Martín-Ferrero MA, Del Canto F, Alberca M, García V, Munar A, Orozco L, Soler R, Fuertes JJ, Huguet M, Sánchez A, García-Sancho J. 2015. Treatment of knee osteoarthritis with allogeneic bone marrow mesenchymal stem cells: a randomized controlled trial. Transplantation 99: 1681-1690.

 

Vendrell V, López-Hernández I, Durán Alonso MB, Feijoo-Redondo A, Abello G, Gálvez H, Giráldez F, Lamonerie T, Schimmang T. 2015. Otx2 is a target of N-myc and acts as a suppressor of sensory development in the mammalian cochlea. Development 142: 2792-800.

 

del Caño-Espinel M, Acebes JR, Sanchez D, Ganfornina MD. 2015. Lazarillo-related lipocalins confer long-term protection against type I spinocerebellar ataxia degeneration contributing to optimize selective autophagy. Mol Neurodegener. 10: 11.

 

Diez-Hermano S, Valero J, Rueda C, Ganfornina MD, Sanchez D. 2015. An automated image analysis method to measure regularity in biological patterns: a case study in a Drosophila neurodegenerative model. Mol. Neurodegener. 10: 9.

 

Sánchez D, Bajo-Grañeras R, Del Caño-Espinel M, Garcia-Centeno R, Garcia-Mateo N, Pascua-Maestro R, Ganfornina MD. 2015. Aging without Apolipoprotein D: molecular and cellular modifications in the hippocampus and cortex. Exp Gerontol. 67: 19-47.

 

Li H, Ruberu K, Muñoz SS, Jenner AM, Spiro A, Zhao H, Rassart E, Sanchez D, Ganfornina MD, Karl T, Garner B. 2015. Apolipoprotein D modulates amyloid pathology in APP/PS1 Alzheimer's disease mice. Neurobiol. Aging 36: 1820-1833.

 

Acedo A, Hernández-Moro C, Curiel-García Á, Díez-Gómez B, Velasco EA. 2015. Functional classification of BRCA2 DNA variants by splicing assays in a large minigene with 9 exons. Hum. Mutat. 36: 210-221.

 

Alonso S, González B, Ruiz-Larroya T, Durán Domínguez M, Kato T, Matsunaga A, Suzuki K, Strongin AY, Gimènez-Bonafé P, Perucho M. 2015. Epigenetic inactivation of the extracellular matrix metallopeptidase ADAMTS19 gene and the metastatic spread in colorectal cancer. Clin Epigenetics 7: 124.

 

Rebbeck TR, Mitra N, Wan F, … Durán M… (333 autores en total). 2015. Association of type and location of BRCA1 and BRCA2 mutations with risk of breast and ovarian cancer. J. Am. Med. Assoc. 313: 1347-1361.

 

de Juan I, Palanca S, Domenech A, Feliubadaló L, Segura Á, Osorio A, Chirivella I, de la Hoya M, Sánchez AB, Infante M, Tena I, Díez O, Garcia-Casado Z, Vega A, Teulé À, Barroso A, Pérez P, Durán M, Carrasco E, Juan-Fita MJ, Murria R, Llop M, Barragan E, Izquierdo Á, Benítez J, Caldés T, Salas D, Bolufer P. 2015. BRCA1 and BRCA2 mutations in males with familial breast and ovarian cancer syndrome. Results of a Spanish multicenter study. Fam. Cancer 14: 505-513.

 

Seguí N, Mina LB, Lázaro C, Sanz-Pamplona R, Pons T, Navarro M, Bellido F, López-Doriga A, Valdés-Mas R, Pineda M, Guinó E, Vidal A, Soto JL, Caldés T, Durán M, Urioste M, Rueda D, Brunet J, Balbín M, Blay P, Iglesias S, Garré P, Lastra E, Sánchez-Heras AB, Valencia A, Moreno V, Pujana MÁ, Villanueva A, Blanco I, Capellá G, Surrallés J, Puente XS, Valle L. 2015. Germline mutations in FAN1 cause hereditary colorectal cancer by impairing DNA repair. Gastroenterology 149: 563-566.

 

Tullius SG, Biefer HR, Li S, Trachtenberg AJ, Edtinger K, Quante M, Krenzien F, Uehara H, Yang X, Kissick HT, Kuo WP, Ghiran I, de la Fuente MA, Arredouani MS, Camacho V, Tigges JC, Toxavidis V, El Fatimy R, Smith BD, Vasudevan A, Elkhal A. 2015. NAD+ protects against EAE by regulating CD4+ T-cell differentiation. Nat. Commun. 5: 5101.

 

García-Rostán G, Tallini G, Salvatore G. 2015. Anaplastic thyroid carcinoma: molecular tools for diagnosis and therapy. Int. J. Endocrinol. 2015: 341725.

 

 

 

 

Resumen de la producción

 

 

CMP

I3U

MGD

Total IBGM

Número total de artículos

23

9

14

        46

Número de artículos en el primer cuartil

7 (30%)

4 (44%)

10 (71%)

21 (46%)

 

 

IBGM

Instituto De Biología Y Genética Molecular.
Calle Sanz y Forés, 3, 47003 Valladolid. Ver mapa