PUBLICACIONES DEL IBGM EN EL AÑO 2011

(en revistas indexadas en PubMed)

 

Fisiología Celular y Molecular (MCP)

Muñoz E, Valero RA, Quintana A, Hoth M, Núñez L, Villalobos C. 2011. Nonsteroidal anti-inflammatory drugs inhibit vascular smooth muscle cell proliferation by enabling the Ca²⁺-dependent inactivation of calcium release-activated calcium/Orai channels normally prevented by mitochondria. J. Biol. Chem. 286: 16186-16196.

Quintana A, Pasche M, Junker C, Al-Ansary D, Rieger H, Kummerow C, Núñez L, Villalobos C, Meraner P, Becherer U, Rettig J, Niemeyer BA, Hoth M. 2011. Calcium microdomains at the immunological synapse: how ORAI channels, mitochondria and calcium pumps generate local calcium signals for efficient T-cell activation. EMBO J. 30: 3895-3902.

Molina-Guijarro JM, Macías A, García C, Muñoz E, García-Fernández LF, David M, Lillo MP, Núñez L, Martínez-Leal JF, Moneo V, Cuevas C, Villalobos C, Valenzuela C, Galmarini CM. 2011. Irvalec inserts in the plasma membrane, causing rapid loss of integrity and necrotic cell death in tumor cells. PLoS One 6: e19042.

Núñez J, Sanz-Blasco S, Vignoletti F, Muñoz F, Arzate H, Villalobos C, Núñez L, Caffesse RG, Sanz M. 2011. Periodontal regeneration following implantation of cementum and periodontal ligament-derived cells. J. Periodontal Res. 47: 33-44.

Orozco L, Soler R, Morera C, Alberca M, Sánchez A, García-Sancho J. 2011. Intervertebral disc repair by autologous mesenchymal bone marrow cells: a pilot study. Transplantation 92: 822-828.

Gallego-Sandín S, Alonso MT, García-Sancho J. Calcium homoeostasis modulator 1 (CALHM1) reduces the calcium content of the endoplasmic reticulum (ER) and triggers ER stress. Biochem. J. 437: 469-475, 2011.

Alonso MT, García-Sancho J. 2011. Nuclear Ca²⁺ signalling. Cell Calcium 49: 280-289.

Aulestia FJ, Redondo PC, Rodríguez-García A, Rosado JA, Salido GM, Alonso MT, García-Sancho J. 2011. Two distinct calcium pools in the endoplasmic reticulum of HEK-293T cells. Biochem. J. 435: 227-235.

Manjarrés IM, Alonso MT, García-Sancho J. 2011. Calcium entry-calcium refilling (CECR) coupling between store-operated Ca²⁺ entry and sarco/endoplasmic reticulum Ca²⁺-ATPase. Cell Calcium 49: 153-61.

Frazziano G; Moreno L, Moral-Sanz J, Menendez C, Escolano L, Gonzalez C, Villamor E, Cogolludo A, Perez-Vizcaino F. 2011. Neutral sphingomyelinase, NADPH oxidase and reactive oxygen species. Role in acute hypoxic pulmonary vasoconstriction. J. Cell. Physiol. 226: 2633-2640.

Monteiro TC, Batuca JR, Obeso A, Gonzalez C, Monteiro EC. 2011. Carotid body function in aged rats: responses to hypoxia, ischemia, dopamine, and adenosine. Age 33: 337-350.

Gonzalez-Martin MC, Vega-Agapito MV, Obeso A, Prieto-Lloret J, Bustamante R, Castañeda J, Agapito MT, Gonzalez C. Moderate ethanol ingestion, redox status and cardiovascular system in the rat. Alcohol 45: 391-395, 2011.

Gonzalez-Martín M.C, Vega-Agapito M.V, Conde, S, Castañeda J, Bustamante R, Olea E, Perez-Vizcaino F, Gonzalez C, Obeso A. 2011. Carotid body function and ventilatory responses in intermittent hypoxia. Evidence for anomalous brainstem integration of arterial chemoreceptor input. J. Cell. Physiol. 226: 1961-1969.

Olea E, Ferrer E, Prieto-Lloret J, Gonzalez-Martin MC, Vega-Agapito MV, Gonzalez-Obeso E, Agapito MT, Peinado V, Obeso A, Barbera JA, Gonzalez C. 2011. Effects of cigarette smoke and chronic hypoxia on airways remodeling and resistance. Clinical significance. Respir. Physiol. Neurobiol. 179: 305-313.

Ferrer E, Peinado V, Castañeda J, Prieto-Lloret J, Olea E, Gonzalez-Martin MC, Vega-Agapito MV, Diez M, Obeso A, Gonzalez C, Barbera JA. 2011. Effects of chronic cigarette smoke and hypoxia exposure on the pulmonary circulation in the guinea pig. Eur. Respir. J. 38: 617-627.

Liu X, He L, Dinger B, Gonzalez C, Stensaas L, Fidone S. 2011. A chronic pain: Inflammation-dependent chemoreceptor adaptation in rat carotid body. Respir. Physiol. Neurobiol. 178: 362-369.

Conde SV, Nunes da Silva T, Gonzalez C, Mota Carmo M, Monteiro EC, Guarino MP. 2011. Chronic caffeine intake decreases circulating catecholamines and prevents diet-induced  insulin resistance and hypertension in rats. Br. J. Nutr. 107: 86-95.

Rocher A, Caceres AI, Obeso A, Gonzalez C. 2011. Tetrodotoxin as a tool to elucidate sensory transduction mechanisms: the case for the arterial chemoreceptors of the carotid body. Mar. Drugs 9: 2683-2704.

Cayzac SH, Rocher A, Obeso A, Gonzalez C, Iccardi D, Kemp PJ. 2011. Spermine attenuates carotid body glomus cell oxygen sensing by inhibiting L-type Ca channels. Respir. Physiol. Neurobiol. 175: 317-330.

Ferruelo A, El-Assar M, Lorente JA, Nin N, Peñuelas O, Fernández-Segoviano P, Gonzalez C, Esteban A. 2011. Transcriptional profiling and genotyping of degraded nucleic acids from autopsy tissue samples after prolonged formalin fixation times. Int. J. Clin. Exp. Pathol. 4: 156-161.

del Barrio, L., Egea, J., León, R., Romero, A., Ruiz, A., Montero, M., Alvarez, J. and López, M.G. 2011. Calcium signaling mediated through α7 and non-α7 nAChR stimulation is differentially regulated in bovine chromaffin cells to induce catecholamine release. Br. J. Pharmacol. 162 94-109.

 

Inmunidad Innata e Inflamación (I3U)

Dickinson RJ, Delavaine L, Cejudo-Marín R, Stewart G, Staples CJ, Didmon MP, Trinidad AG, Alonso A, Pulido R, Keyse SM. 2011. Phosphorylation of the kinase interaction motif in mitogen-activated protein (MAP) kinase phosphatase-4 mediates cross-talk between protein kinase A and MAP kinase signaling pathways. J. Biol. Chem. 286: 38018-38026.

Fernández-Salazar L, Álvarez-Quiñones M, González Hernández JM, Fraile A, Mayor E, Arranz E, Garrote JA. 2011. IFN b1b induced celiac disease. Scand. J. Gastroenterol. 46: 1525-1526.

Astudillo, A. M., Pérez-Chacón, G., Balgoma, D., Gil de Gómez, L., Ruipérez, V., Guijas, C., Balboa, M. A. & Balsinde, J. 2011. Influence of cellular arachidonic acid levels on phospholipid remodeling and CoA‐independent transacylase activity in human monocytes and U937 cells. Biochim. Biophys. Acta 1811: 97-103.

Barroso, G., Rodríguez-Calvo, R., Serrano-Marco, L., Astudillo, A. M., Balsinde, J., Palomer, X. & Vázquez-Carrera, M. 2011. The PPARb/d activator GW501516 prevents the down-regulation of AMPK caused by a high-fat diet in liver and amplifies the PGC-1a-lipin 1-PPARa pathway leading to increased fatty acid oxidation. Endocrinology 152: 1848-1859.

Valdearcos, M., Esquinas, E., Meana, C., Gil de Gómez, L., Guijas, C., Balsinde, J. & Balboa, M. A. 2011. Subcellular localization and role of lipin‐1 in human macrophages. J. Immunol. 186: 6004-6013.

Bosch, M., Marí, M., Herms, A., Fernández, A.,  Fajardo, A.,  Kassan, A., Giralt, A., Colell, A., Balgoma, D., Barbero, E., González-Moreno, E., Matías, N., Tebar, F., Balsinde, J., Camps, M., Enrich, C., Gross, S. P., García-Ruiz, C., Pérez-Navarro, E., Fernández-Checa, J. C., & Pol, A. 2011. Caveolin-1 deficiency causes cholesterol-dependent  mitochondrial dysfunction and apoptotic susceptibility. Curr. Biol. 21: 681-686.

Astudillo, A. M., Pérez-Chacón, G., Meana, C., Balgoma, D., Pol, A., del Pozo, M. A., Balboa, M. A. & Balsinde, J. 2011. Altered arachidonate distribution in macrophages from caveolin-1 null mice leading to a compromised inflammatory response in vivo. J. Biol. Chem. 286: 35299-35307.

Francisco V, Figueirinha A, Neves BM, García-Rodríguez C, Lopes MC, Cruz MT, Batista T. 2011. Cymbopogon citratus as source of new and safe anti-inflammatory drugs: bio-guided assay using lypolysaccharide-stimulated macrophages. J. Ethnopharmacol. 133: 818-827.

Municio C, Hugo E, Alvarez Y, Alonso S, Blanco L, Fernández N, Sánchez Crespo M. 2011. Apoptotic cells enhance IL-10 and reduce IL-23 production in human dendritic cells treated with zymosan. Mol. Immunol. 49: 97-106.

Alvarez Y, Municio C, Hugo E, Zhu J, Alonso S, Hu X, Fernández N, Sánchez Crespo M. 2011. Notch- and transducin-like enhancer of split (TLE)-dependent histone deacetylation explain interleukin 12 (IL-12) p70 inhibition by zymosan. J. Biol. Chem. 286: 16583-16595.

 

Genética Molecular de la Enfermedad (MGD)

Madrigal I, Xunclá M, Tejada MI, Fernandez-Carvajal I, Perez-Jurado LA, Rodriguez-Revenga L, Milá M. 2011. FMR1 alleles and cognitive and/or behaviour phenotypes. Eur. J. Hum. Genet. 19: 921-923.

Bustamante J, Tamayo E, Flórez S, Telleria JJ, Bustamante E, López J, San Román JA, Alvarez FJ. 2011. Toll-like receptor 2 R753Q polymorphisms are associated with an increased risk of infective endocarditis. Rev. Esp. Cardiol. 64: 1056-1059.

Ayuso C, Tellería JJ, Tejedor JC, Gracia. 2011. Ethics on genetic research. Med. Clin. (Barcelona) 137: 22-25.

de Felipe MM, Feijoo Redondo AF, García-Sancho J, Schimmang T, Alonso MB. 2011. Cell- and gene-therapy approaches to inner ear repair. Histol. Histopathol. 26: 923-940.

Lubka-Pathak M, Shah AA, Gallozzi M, Müller M, Zimmermann U, Löwenheim H, Pfister M, Knipper M, Blin N, Schimmang T. 2011. Altered expression of securin (Pttg1) and serpina3n in the auditory system of hearing-impaired Tff3-deficient mice. Cell. Mol. Life Sci. 68: 2739-2749.

Domínguez-Frutos E, López-Hernández I, Vendrell V, Neves J, Gallozzi M, Gutsche K, Quintana L, Sharpe J, Knoepfler PS, Eisenman RN, Trumpp A, Giráldez F, Schimmang T. 2011. N-myc controls proliferation, morphogenesis, and patterning of the inner ear. J. Neurosci. 31: 7178-7189.

Pérez-Cabornero L; Borrás E, Infante M; Velasco EA, Acedo A, Lastra E, Cuevas J, Pineda M; Ramón y Cajal T, Capellá G, Miner C, Durán M. 2011. Characterization of new founder Alu-mediated rearrangements in MSH2 gene associated with a Lynch Syndrome phenotype. Cancer Prev. Res. 4: 1546-1555.

Pérez-Cabornero L; Infante M; Velasco EA; Lastra E, Acedo A, Miner C; Durán M. 2011. Frequency of Rearrangements in Lynch Syndrome cases associated to MSH2. Characterization of a new deletion involving both EPCAM and the 5´part of MSH2. Cancer Prev. Res. 4: 1556-1562.

de la Fuente MA, Recher M, Rider NL, Strauss KA, Morton DH, Adair M, Bonilla FA, Ochs HD, Gelfand EW, Pessach IM, Walter JE, King A, Giliani S, Pai SY, Notarangelo LD. 2011. Reduced thymic output, cell cycle abnormalities, and increased apoptosis of T lymphocytes in patients with cartilage-hair hypoplasia. J. Allerg. Clin. Immunol. 128: 139-146.

P. Salerno, G. Garcia-Rostan, S. Piccinin, TC. Bencivenga, G. Di Maro, C. Doglioni, F. Basolo, R. Maestro, A. Fusco, M. Santoro, G. Salvatore. 2011. TWIST1 plays a pleiotropic role in determining the anaplastic thyroid cancer phenotype. J. Clin. Endoc. Metabol. 96: E772-E776.

Garcia-Rostan G, M. Sobrinho-Simoes. 2011. Poorly differentiated thyroid carcinoma: an evolving entity. Diag. Cytopathol. 17: 114-118.

Bajo-Grañeras R, Sanchez D, Gutierrez G, Gonzalez C, Carmo SD, Rassart E, Ganfornina MD. 2011. Apolipoprotein D alters the early transcriptional response to oxidative stress in the adult cerebellum. J. Neurochem. 117: 949-960.

Bajo-Grañeras R, Ganfornina MD, Martín-Tejedor E, Sanchez D. 2011. Apolipoprotein D mediates autocrine protection of astrocytes and controls their reactivity level, contributing to the functional maintenance of paraquat-challenged dopaminergic systems. Glia 59: 1551-1566.

Jiménez-Palomares M, Cózar-Castellano I, Ganfornina MD, Sánchez D, Perdomo G. 2011. Genetic deficiency of apolipoprotein D in the mouse is associated with nonfasting hypertriglyceridemia and hyperinsulinemia. Metabolism 60: 1767-1774.

Ruiz M, Sanchez D, Canal I, Acebes A, Ganfornina MD. 2011. Sex-dependent modulation of longevity by two Drosophila homologues of human Apolipoprotein D, GLaz and NLaz. Exp. Gerontol. 46: 579-589.

Mulligan AM, Couch FJ, Barrowdale D, et al (192 autores). 2011. Common breast cancer susceptibility alleles are associated with tumor subtypes in BRCA1 and BRCA2 mutation carriers: results from the Consortium of Investigators of Modifiers of BRCA1/2. Breast Cancer Res. 20: 14-31.

Im KM, Kirchhoff T, Wang X, et al (121 autores). 2011. Haplotype structure in Ashkenazi Jewish BRCA1 and BRCA2 mutation carriers. Hum. Genet. 5: 685-698.

Ramus SJ, Kartsonaki C, Gayther SA, et al (163 autores). 2011. Genetic Variation at 9p22.2 and Ovarian Cancer Risk for BRCA1 and BRCA2 Mutation Carriers. J. Natl. Cancer Inst. 2: 105-115.

Peixoto A, Santos C, Pinheiro M, et al (65 autores). 2011. International distribution and age estimation of the Portuguese BRCA2 c.156_157insAlu founder mutation. Breast Cancer Res. Treat. 127: 671-679.

 

 

Resumen de la producción

 

	CMP	I3U	MGD	Total IBGM
Número total de artículos	21	10	18	49
Número de artículos en el primer cuartil	10 (48%)	8 (80%)	12 (67%)	30 (61%)