INNER EAR DEVELOPMENT

Institute for Biology and Molecular Genetics
Thomas Schimmang
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publications since 2003


I. Vicario and T. Schimmang. (2003) Transfer of FGF-2 via HSV-1-based amplicon vector promotes efficient formation of neurons from embryonic stem cells. J. Neurosci. Meth. 15, 55-60.

T. Schimmang, J. Tan, M. Müller, U. Zimmermann, K. Rohbock, I. Köpschall, A. Limberger, L. Minichiello and M. Knipper. (2003) Lack of BDNF and TrkB signaling leads to a spatial reinnervation reshaping of innervation and hearing loss. Development 130, 4741-4750.

Y. Alvarez, M.T. Alonso, V. Vendrell, L. Zelarayan, P. Chamero, T. Theil, M. Bösl, S. Kato, M. Maconochie and T. Schimmang. (2003) Requirements for FGF-3 and FGF-10 during inner ear formation. Development 130, 6329-6338.

N. Powles, C. Babbs, M. Ficker, T. Schimmang and M. Maconochie. (2004). Identification and anlysis of genes from the mouse otic vesicle and their association with developmental subprocesses through in situ hybridisation. Dev. Biol. 268, 24-38.

E. Carnicero, L.C. Zelarayan, L. Ruttiger, M. Knipper, Y. Alvarez, M.T. Alonso  and T. Schimmang (2004). Differential roles of fibroblast growth factor-2 during development and maintenance of auditory sensory epithelia. J. Neurosci. Res. 77, 787-797. 

D. Riethmacher, F.Lim and T. Schimmang. (2006). Efficient transfer of HSV-1 amplicon vectors into ES cells and their derivatives. 
Meth. Mol. Biol. 329, 263-272.

O. Lioubinski, M. T. Alonso, Y. Alvarez, V. Vendrell, Garrosa M., P. Murpy and T. Schimmang. (2006). FGF signalling controls expression of vomeronasal recptors during embryogenesis. 
Mech. Dev. 123, 17-23.

V.S. Aggarwal, J. Liao, A. Bondarev, T. Schimmang, M. Lewandoski, J. Locker, A. Shanske, M. Campione and B. Morrow. (2006). Dissection of Tbx1 and Fgf interactions in mouse models of 22q11DS suggests functional redundancy.
Hum. Mol. Genet. 15, 3219-3228.

*L. Rüttiger, *R. Panford-Walsh *T. Schimmang, J. Tan, U. Zimmermann, K. Rohbock, I. Köpschall, A. Limberger, M. Müller, J.–T. Fraenzer, J. Cimerman, and M. Knipper. (2007). BDNF mRNA expression and protein localization are changed in age-related hearing loss.
*Equal contribution 
Neurobiol. of Aging 28, 586-60.

L.C. Zelarayan, V. Vendrell, Y. Alvarez, E. Dominguez-Frutos, T. Theil, M.T. Alonso, M. Maconochie and T. Schimmang, (2007). Differential requirements for FGF3, FGF8 and FGF10 during inner ear development. 
Dev.Biol. 308, 379-91. 

X.P. Wang, M. Soumalainen, S. Felszeghy, L.C. Zelarayan, M.T. Alonso, M.V. Plikus, R.L. Maas, C.-M. Chuong, T. Schimmang and I. Thesleff. (2007). An integrated gene regulatory network controls stem cell proliferation in teeth. 
PloS Biol. 5, e159

T. Schimmang. (2007). Expression and functions of FGF ligands during early otic development.
Int J Dev Biol. 51, 473-81.

M. Praetorius, I. Vicario and T. Schimmang. Efficient transfer of embryonic stem cells into the cochlea via a non-invasive vestibular route.
Acta Otlolaryngol., in press