Publications since 2011

Meis2 Is Required for Inner Ear Formation and Proper Morphogenesis of the Cochlea. Durán Alonso MB, Vendrell V, López-Hernández I, Alonso MT, Martin DM, Giráldez F, Carramolino L, Giovinazzo G, Vázquez E, Torres M, Schimmang T.
Front Cell Dev Biol. 2021 May 28;9:679325.

Deletion of BDNF in Pax2 Lineage-Derived Interneuron Precursors in the Hindbrain Hampers the Proportion of Excitation/Inhibition, Learning, and Behavior. Eckert P, Marchetta P, Manthey MK, Walter MH, Jovanovic S, Savitska D, Singer W, Jacob MH, Rüttiger L, Schimmang T, Milenkovic I, Pilz PKD, Knipper M.
Front Mol Neurosci. 2021 Mar 26;14:642679.

Age-Dependent Auditory Processing Deficits after Cochlear Synaptopathy Depend on Auditory Nerve Latency and the Ability of the Brain to Recruit LTP/BDNF. Marchetta P, Savitska D, Kübler A, Asola G, Manthey M, Möhrle D, Schimmang T, Rüttiger L, Knipper M, Singer W.
Brain Sci. 2020 Oct 6;10(10):710.

Differential deletion of GDNF in the auditory system leads to altered sound responsiveness. Harasztosi C, Wolter S, Gutsche K, Durán-Alonso MB, López-Hernández I, Pascual A, López-Barneo J, Knipper M, Rüttiger L, Schimmang T.
J Neurosci Res. 2020 Sep;98(9):1764-1779.

Lower ototoxicity and absence of hidden hearing loss point to gentamicin C1a and apramycin as promising antibiotics for clinical use. Ishikawa M, García-Mateo N, Čusak A, López-Hernández I, Fernández-Martínez M, Müller M, Rüttiger L, Singer W, Löwenheim H, Kosec G, Fujs Š, Martínez-Martínez L, Schimmang T, Petković H, Knipper M, Durán-Alonso MB.
Sci Rep. 2019 Feb 20;9(1):2410.

Myc is dispensable for cardiomyocyte development but rescues Mycn-deficient hearts through functional replacement and cell competition. Muñoz-Martín N, Sierra R, Schimmang T, Villa Del Campo C, Torres M.
Development. 2019 Feb 1;146(3).

BDNF-Live-Exon-Visualization (BLEV) Allows Differential Detection of BDNF Transcripts in vitro and in vivo. Singer W, Manthey M, Panford-Walsh R, Matt L, Geisler HS, Passeri E, Baj G, Tongiorgi E, Leal G, Duarte CB, Salazar IL, Eckert P, Rohbock K, Hu J, Strotmann J, Ruth P, Zimmermann U, Rüttiger L, Ott T, Schimmang T, Knipper M.
Front Mol Neurosci. 2018 Sep 27;11:325.

Visualizing BDNF Transcript Usage During Sound-Induced Memory Linked Plasticity. Matt L, Eckert P, Panford-Walsh R, Geisler HS, Bausch AE, Manthey M, Müller NIC, Harasztosi C, Rohbock K, Ruth P, Friauf E, Ott T, Zimmermann U, Rüttiger L, Schimmang T, Knipper M, Singer W.
Front Mol Neurosci. 2018 Jul 31;11:260.

Transcription factor induced conversion of human fibroblasts towards the hair cell lineage. Duran Alonso MB, Lopez Hernandez I, de la Fuente MA, Garcia-Sancho J, Giraldez F, Schimmang T.
PLoS One. 2018 Jul 6;13(7):e0200210.

Gαi Proteins are Indispensable for Hearing. Beer-Hammer S, Lee SC, Mauriac SA, Leiss V, Groh IAM, Novakovic A, Piekorz RP, Bucher K, Chen C, Ni K, Singer W, Harasztosi C, Schimmang T, Zimmermann U, Pfeffer K, Birnbaumer L, Forge A, Montcouquiol M, Knipper M, Nürnberg B, Rüttiger L.
Cell Physiol Biochem. 2018;47(4):1509-1532.

An FGF3-BMP Signaling Axis Regulates Caudal Neural Tube Closure, Neural Crest Specification and Anterior-Posterior Axis Extension. Anderson MJ, Schimmang T, Lewandoski M.
PLoS Genet. 2016 May 4;12(5):e1006018. doi: 10.1371/journal.pgen.1006018. eCollection 2016 May.

BDNF in Lower Brain Parts Modifies Auditory Fiber Activity to Gain Fidelity but Increases the Risk for Generation of Central Noise After Injury. Chumak T, Rüttiger L, Lee SC, Campanelli D, Zuccotti A, Singer W, Popelář J, Gutsche K, Geisler HS, Schraven SP, Jaumann M, Panford-Walsh R, Hu J, Schimmang T, Zimmermann U, Syka J, Knipper M.
Mol Neurobiol. 2016 Oct;53(8):5607-27. doi: 10.1007/s12035-015-9474-x. Epub 2015 Oct 17.

Gene expression profiling of the inner ear. Schimmang T, Maconochie M.
J Anat. 2016 Feb;228(2):255-69. doi: 10.1111/joa.12376. Epub 2015 Sep 25. Review.

Otx2 is a target of N-myc and acts as a suppressor of sensory development in the mammalian cochlea. Vendrell V, López-Hernández I, Durán Alonso MB, Feijoo-Redondo A, Abello G, Gálvez H, Giráldez F, Lamonerie T, Schimmang T.
Development. 2015 Aug 15;142(16):2792-800. doi: 10.1242/dev.122465. Epub 2015 Jul 9.

Is there a relationship between brain-derived neurotrophic factor for driving neuronal auditory circuits with onset of auditory function and the changes following cochlear injury or during aging? Schimmang T, Durán Alonso B, Zimmermann U, Knipper M.
Neuroscience. 2014 Dec 26;283:26-43. doi: 10.1016/j.neuroscience.2014.07.025. Epub 2014 Jul 24. Review.

Progressive effects of N-myc deficiency on proliferation, neurogenesis, and morphogenesis in the olfactory epithelium. Wittmann W, Schimmang T, Gunhaga L.
Dev Neurobiol. 2014 Jun;74(6):643-56. doi: 10.1002/dneu.22162. Epub 2014 Jan 16.

L-type CaV1.2 deletion in the cochlea but not in the brainstem reduces noise vulnerability: implication for CaV1.2-mediated control of cochlear BDNF expression. Zuccotti A, Lee SC, Campanelli D, Singer W, Satheesh SV, Patriarchi T, Geisler HS, Köpschall I, Rohbock K, Nothwang HG, Hu J, Hell JW, Schimmang T, Rüttiger L, Knipper M.
Front Mol Neurosci. 2013 Aug 9;6:20. doi: 10.3389/fnmol.2013.00020. eCollection 2013.

Coupling the cell cycle to development and regeneration of the inner ear. Schimmang T, Pirvola U.
Semin Cell Dev Biol. 2013 May;24(5):507-13. doi: 10.1016/j.semcdb.2013.04.004. Epub 2013 May 9. Review.

Generation of inner ear sensory cells from bone marrow-derived human mesenchymal stem cells. Durán Alonso MB, Feijoo-Redondo A, Conde de Felipe M, Carnicero E, García AS, García-Sancho J, Rivolta MN, Giráldez F, Schimmang T.
Regen Med. 2012 Nov;7(6):769-83. doi: 10.2217/rme.12.65.

Transcription factors that control inner ear development and their potential for transdifferentiation and reprogramming. Schimmang T.
Hear Res. 2013 Mar;297:84-90. doi: 10.1016/j.heares.2012.11.001. Epub 2012 Nov 14. Review.

Noise-induced inner hair cell ribbon loss disturbs central arc mobilization: a novel molecular paradigm for understanding tinnitus. Singer W, Zuccotti A, Jaumann M, Lee SC, Panford-Walsh R, Xiong H, Zimmermann U, Franz C, Geisler HS, Köpschall I, Rohbock K, Varakina K, Verpoorten S, Reinbothe T, Schimmang T, Rüttiger L, Knipper M.
Mol Neurobiol. 2013 Feb;47(1):261-79. doi: 10.1007/s12035-012-8372-8. Epub 2012 Nov 16.

Roles of Wnt8a during formation and patterning of the mouse inner ear. Vendrell V, Vázquez-Echeverría C, López-Hernández I, Alonso BD, Martinez S, Pujades C, Schimmang T.
Mech Dev. 2013 Feb;130(2-3):160-8. doi: 10.1016/j.mod.2012.09.009. Epub 2012 Oct 4.

Lack of brain-derived neurotrophic factor hampers inner hair cell synapse physiology, but protects against noise-induced hearing loss. Zuccotti A, Kuhn S, Johnson SL, Franz C, Singer W, Hecker D, Geisler HS, Köpschall I, Rohbock K, Gutsche K, Dlugaiczyk J, Schick B, Marcotti W, Rüttiger L, Schimmang T, Knipper M.
J Neurosci. 2012 Jun 20;32(25):8545-53. doi: 10.1523/JNEUROSCI.1247-12.2012.

Cell and tissue therapy in regenerative medicine. Sánchez A, Schimmang T, García-Sancho J.
Adv Exp Med Biol. 2012;741:89-102. doi: 10.1007/978-1-4614-2098-9_7.

Cell- and gene-therapy approaches to inner ear repair. Conde de Felipe MM, Feijoo Redondo A, García-Sancho J, Schimmang T, Durán Alonso MB.
Histol Histopathol. 2011 Jul;26(7):923-40. doi: 10.14670/HH-26.923. Review.

N-myc controls proliferation, morphogenesis, and patterning of the inner ear. Domínguez-Frutos E, López-Hernández I, Vendrell V, Neves J, Gallozzi M, Gutsche K, Quintana L, Sharpe J, Knoepfler PS, Eisenman RN, Trumpp A, Giráldez F, Schimmang T.
J Neurosci. 2011 May 11;31(19):7178-89. doi: 10.1523/JNEUROSCI.0785-11.2011.

Altered expression of securin (Pttg1) and serpina3n in the auditory system of hearing-impaired Tff3-deficient mice. Lubka-Pathak M, Shah AA, Gallozzi M, Müller M, Zimmermann U, Löwenheim H, Pfister M, Knipper M, Blin N, Schimmang T.
Cell Mol Life Sci. 2011 Aug;68(16):2739-49. doi: 10.1007/s00018-010-0586-1. Epub 2010 Nov 15.