PUBLICATIONS BY C. VILLALOBOS AND L. NÚÑEZ.
2002 - 2006
	Cell proliferation depends on mitochondrial Ca2+ uptake: inhibition by salicylate. Núñez L, Valero RA, Senovilla L, Sanz-Blasco S, García-Sancho J, Villalobos C (2006). J Physiol 571, 57-73. Changes in expression of hypothalamic releasing hormone receptors in individual rat anterior pituiatry cells during maturation, puberty and senescence. Senovilla L, García-Sancho J, Villalobos C (2005). Endocrinology 146, 4627-4634. Bioluminescence imaging of nuclear calcium oscillations in intact pancreatic islets of Langerhans from the mouse. Villalobos C, Nadal A, Núñez L, Quesada I, Chamero P, Alonso MT, García-Sancho J (2005). Cell Calcium 38, 131-139.   Multifunctional cells in human pituitary adenomas: implications for paradoxical secretion and tumorigenesis. Senovilla L, Núñez L, de Campos JM, de Luis DA, Romero E, Sánchez A, García-Sancho J, Villalobos C (2004). J Clin Endocrinol Metab  89, 4545-4552.   Phenotypic characterization of multifunctional somatotropes, mammotropes and gonadotropes of the mouse anterior pituitary. Villalobos C, Núñez L, García-Sancho J (2004). Pflügers Arch 449, 257-264. Anterior pituitary thyrotropes are multifunctional cells. Villalobos C, Núñez L, García-Sancho J (2004). Am J Physiol 287, E1166-E1170. Multifunctional cells of mouse anterior pituitary reveal a striking sexual dimorphism. Núñez L, Villalobos C, Senovilla L, García-Sancho J (2003). J Physiol (London) 549, 835-843. Fura-2 antagonises calcium-induced calcium release. Alonso MT, Chamero P, Villalobos C, García-Sancho J (2003). Cell Calcium 33, 27-35. Dampening of cytosolic Ca2+ oscillations on propagation to nucleus. Chamero P, Villalobos C, Alonso MT, García-Sancho J (2002). J Biol Chem 277, 50226-50229. Calcium dynamics and resting transcriptional activity regulates prolactin gene expression. Villalobos C, Núñez L, Faught WJ, Leaumont DC, Boockfor FR, Frawley LS (2002). Endocrinology  143, 3548-3554. Effect of inositol 1,4,5-trisphosphate receptor stimulation on mitochondrial [Ca2+] and secretion  in chromaffin cells. Montero M, Alonso MT, Albillos A, Cuchillo-Ibáñez I, Olivares R, Villalobos C, Alvarez J. (2002). Biochem J 365, 451-459. An extracellular sulfydryl group modulates background sodium conductance and cytosolic calcium in several pituitary cell types. Fonteriz RI, Villalobos C, García-Sancho J (2002). Am J Physiol 282, C864-C872. Redistribution of Ca2+ among cytosol and organella during stimulation of bovine chromaffin cells. Villalobos C, Núñez L, Montero M, García AG, Alonso MT, Chamero P, Alvarez J,  García-Sancho J (2002). FASEB J  16, 343-353.
1997 - 2001
	Mitochondrial [Ca2+] oscillations driven by local high-[Ca2+] domains generated by spontaneous electric activity. Villalobos C, Núñez L, Chamero P, Alonso MT, García-Sancho J (2001). J Biol Chem  276, 40293-40297. Direct actions of adrenergic agents on rat anterior pituitary cells. Alarcón P, Núñez L and García-Sancho J (2001). Pflügers Arch – Eur J Physiol 442, 834-841. The relationship between pulsatile secretion and calcium dynamics in single, living GnRH neurons. Núñez L, Villalobos C, Boockfor FR, Frawley LS (2000). Endocrinology 141, 2012-2017. Dynamics of stimulus-expression coupling as revealed by monitoring of PRL-promoter-driven reporter activity in individual, living mammotropes. Villalobos C, Faught WJ, Frawley LS (1999). Mol Endocrinol 13, 1718-1727. Differential influences of gender and physiologic status on calcium dynamics and prolactin gene expression in rat mammotropes. Gore ACS, Villalobos C, Frawley LS (1999). Endocrine 11 (2), 131-136. Episodic gonadotropin-releasing hormone gene expression revealed by dynamic monitoring of luciferase reporter activity in single, living neurons. Núñez L, Faught WJ, Frawley LS. (1998). Proc Natl Acad Sci USA 95, 9648-9653. a-MSH potentiates the responsiveness of mammotropes by increasing Ca2+ entry. Núñez L, Frawley LS (1998). Am J Physiol 274, E971-E977. Effects of cellular interactions on calcium dynamics in prolactin-secreting cells. Abraham EJ, Villalobos C, Frawley LS (1998). Endocrinology 139, 2988-2993. Dynamic changes of spontaneous [Ca2+]i scillations and their relationship with prolactin gene expression in single, primary mammotropes. Villalobos C, Faught WJ, Frawley LS (1998). Mol Endocrinol 12, 87-95. Multi-responsiveness of single anterior pituitary cells to hypothalamic releasing hormones: a cellular basis for paradoxical secretion. Villalobos C, Núñez L, Frawley LS, García-Sancho J, Sánchez A (1997). Proc Natl Acad Sci USA 94, 14132-14137. Mechanisms for stimulation of anterior pituitary cells by arginine and other amino acids. Villalobos C, Núñez L, García-Sancho J (1997). J Physiol 502, 421-431. Functional ATP receptors in pituitary cells. Villalobos C, Alonso-Torre, SR, Núñez L, García-Sancho J (1997). Am J Physiol 273, C1963-C1971. Extracellular ATP as an autocrine/paracrine regulator of prolactin release. Núñez L, Villalobos C, Frawley LS (1997). Am J Physiol 272, E1117-E1123. Phenotypic characterization and functional correlation of  a-MSH binding to pituitary cells. Zheng T, Villalobos C, Nusser KD, Gettys TW, Faught WJ, Castaño JP and Frawley LS (1997). Am J Physiol 272, E282-E287. Cytosolic phospholipase A2 is coupled to muscarininc receptors in the human astrocitoma cell line 1321N1: characterization of the transducing mechanism. Bayón Y, Hernández M, Alonso A, Núñez L, García-Sancho J, Leslies C, Sánchez-Crespo M, Nieto ML (1997). Biochem J 323, 281-287.
1992 - 1996
	Mechanisms for synchronous calcium oscillations in cultured rat cerebellar neurons. Núñez L, Fonteriz RI, Sánchez A, García-Sancho J (1996). Eur J Neurosci 8, 192-201. Two different constituents of serum stimulate selectively neurons and glia in primary rat cerebellar neurons. Núñez L  and García-Sancho J. (1996). J Physiol 490, 577-583. Enhanced neurite outgrowth of cerebellar granule cells by infection with an HSV-1 vector expressing BDNF. Alonso MT, Lim F, Núñez L, Represa J, Giráldez F, Schimmang T (1996). Neuroreport 7, 3105-3108. Glutamate receptors in the developing cochlear ganglion. Jiménez C, Núñez L  (1996). Int J Dev Biol Suppl 1, 179S-180S. Different contributions of L- and Q-type channels to calcium signals and secretion in chromaffin cell subtypes. Lómax RB, Michelena P, Núñez L, García-Sancho J, García AG, Montiel C (1996). Am J Physiol 272, C476-C484. Functional glutamate receptors in a subpopulation of anterior pituitary cells. Villalobos C, Núñez L, García-Sancho J (1996). FASEB J 10, 654-660. Caffeine-induced oscillations of cytosolic calcium in GH3 pituitary cells are not due to Ca2+ release but to enhanced Ca2+ influx through voltage-gated Ca2+ channels. Villalobos C, García-Sancho J (1996). Pflügers Arch – Eur J Physiol 431, 371-378. Glutamate increases cytosolic calcium in GH3 pituitary cells via a high-affinity glutamate transporter. Villalobos C, García-Sancho J (1995). FASEB J  9, 815-819. Capacitative Ca2+ entry contributes to the calcium influx induced by thyrotropin-releasing hormone (TRH) in GH3 pituitary cells. Villalobos C and García-Sancho J (1995). Pflügers Arch – Eur J Physiol 430, 923-935. Differential Ca2+ responses of adrenergic and noradrenergic bovine chromaffin cells stimulated with verious secretagogues. Núñez L, De la Fuente M, García AG, García-Sancho J (1995). Am J Physiol 269, C1540-C1546. Nitric oxide synthesis in rat peritoneal macrophages is induced by IgE/DNP complex and cyclic AMP analogues. Evidence in favor of a common signaling mechanism. Alonso A, Carvalho J, Alonso-Torre SR, Núñez L, Bosca L, Sánchez-Crespo M (1995). J Immunol 145, 6475-6483. Permeation by zinc of bovine chromaffin cell calcium channels: relevance to secretion. Vega MT, Villalobos C, Garrido B, Gandía L, Bulbena O, García-Sancho J, García AG, Artalejo AR (1994). Pflügers Arch – Eur J Physiol 429, 231-239. The role of the inward rectifying K+ current in resting potential and TRH induced changes in cell excitability of GH3 rat anterior pituitary cells. Barros F, Villalobos C, García-Sancho J, Del Camino D, De la Peña P (1994). Pflügers Arch – Eur J Physiol 426, 221-230. Inhibition of voltage-gated Ca2+ entry into GH3 and chromaffin cells by imidazole antimycotics and other cytochrome P450 blockers. Villalobos C, Fonteriz RI, López MG, García AG, García-Sancho J (1992). FASEB J 6, 2742-2747. Ca2+ influx following receptor activation: P450 might provide signal for state of Ca2+ stores. García-Sancho J, Alvarez J, Montero M, Villalobos C (1992). Trends Pharmacol Sci 13, 12-13. Effects of the antithrombitic agent PCA 4230 on agonist-induced Ca2+ entry and Ca2+ release in human platelets. Alonso MT, Villalobos C, Sánchez A (1992). Biochim Biophys Acta 1104, 257-260.